The V8 engine of the S 500 Cabrio has an output of 335 kW (455 hp). The displacement stands at 4663 cc and the engine produces peak torque of 700 Nm from 1800 rpm.

In NEDC combined mode the Cabrio gets by on 8.5 litres of premium-grade petrol per 100 km, with CO2 emissions of 199 g/km. The innovative 9G-TRONIC 9-speed automatic transmission supports both a dynamic and a fuel-saving driving style. 

It can be set to a sportier or more comfort-oriented mode, according to personal tastes. The four-link front axle impresses with a high level of driving comfort, plus precise suspension action.

Like the S-Class Saloon and Coupé, the new Cabrio is available with numerous new assistance systems that make driving even more comfortable and safer.

 Intelligent Drive systems include PRE-SAFE(r) Brake with pedestrian detection, DISTRONIC PLUS with Steering Assist and Stop&Go Pilot, Brake Assist BAS PLUS with Cross-Traffic Assist, Active Lane Keeping Assist, Adaptive Highbeam Assist Plus and Night View Assist Plus.

In addition to a distance and collision warning function in conjunction with Adaptive Brake Assist, which offers collision protection from speeds as low as 7 km/h, the COLLISION PREVENTION ASSIST PLUS system installed in even the standard vehicle also features an additional function: when a danger of collision persists and the driver fails to respond, the system is able to carry out autonomous braking at speeds of up to more than 100 km/h, thereby reducing the severity of collisions with slower or stopping vehicles.

At speeds of up to around 50 km/h the system also brakes in response to stationary vehicles, and is able to prevent rear-end collisions at up to around 40 km/h.